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The Australasian Registry for Severe Cutaneous Adverse Reactions (AUS-SCAR) – Providing a roadmap for closing the diagnostic, patient, and healthcare gaps for a group of rare drug eruptions

Background: Severe cutaneous adverse reactions (SCAR) are a group of delayed presumed T-cell mediated hypersensitivities associated with significant morbidity and mortality. Despite their shared global healthcare burden and impact, the clinical phenotypes, genomic predisposition, drug causality, and...

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Principais autores: Fiona James, BBiomedSci, Michelle S. Goh, MBBS, Sara Vogrin, MBiostat, Irvin Ng, PhD, Abby P. Douglas, PhD, Natasha E. Holmes, PhD, Kyra YL. Chua, PhD, Joseph De Luca, MBBS, Pooja Sharma, MD, Celia Zubrinich, MPhil, Ar K. Aung, MBBS, Douglas Gin, MBBS, Belinda Lambros, MAdvNursPrac, Chris Baker, MBBS, Peter Foley, MD, Alvin H. Chong, MMed, Francis Thien, MD, Jie S. Fok, MBBS, John Su, MBBS, Laura Scardamaglia, MBBS, Andrew Awad, MD, Steven Tong, PhD, Douglas Johnson, PhD, Jack Godsell, MBBS, Alexis Arasu, MBBS, Sara Barnes, MBA, Samar Ojaimi, PhD, Adrian Mar, MBBS, James Yun, PhD, Nikhita Ange, MBBCh, Winnie W.Y. Tong, PhD, Andrew Carr, DSc, Jacqueline Loprete, PhD, Constance H. Katelaris, PhD, Dana Slape, MBBS, Karuna Keat, MBBS, Timothy A. West, MBBS, Monique Lee, MBBS, William Smith, PhD, Pravin Hissaria, MD, Shireen Sidhu, MBBS, Sonja Janson, MBBS, Sudharsan Venkatesan, MBBS, Jane Davies, PhD, Michael J. Lane, MBBS, Andrew M. Redmond, MBBS, Ivan Robertson, MBBS, Amy Legg, GradDipClinPharm, Suran Fernando, PhD, Therese Boyle, MA, Jamma Li, MPhil, Elizabeth J. Phillips, MD, Heather Cleland, MBBS, Johannes S. Kern, MD, Jason A. Trubiano, PhD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-08-01
coleção:World Allergy Organization Journal
Assuntos:
Delayed hypersensitivity
T-cell mediated hypersensitivity
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Acute generalized exanthematous pustulosis
Drug reaction with eosinophilia and systemic symptoms
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S193945512400067X
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