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Ethacrynic acid decreases expression of proinflammatory intestinal wall cytokines and ameliorates gastrointestinal stasis in murine postoperative ileus

OBJECTIVES: Several compounds characterized by an olefin linkage conjugated to a carbonyl group have anti-inflammatory properties. The diuretic ethacrynic acid (EA) is a compound of this type. Herein, we tested the hypothesis that ethacrynic acid can modulate the development of ileus after bowel man...

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Principais autores: Tomoyuki Harada, Mitchell Fink, Ruy J. Cruz Jr
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier España 2018-10-01
Serier:Clinics
Fag:
Ileus
Gastrointestinal Motility
Ethacrynic Acid
Small Intestine
Inflammation Mediators
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100269&lng=en&tlng=en
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