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Extracellular electrophysiology on clonal human β-cell spheroids

BackgroundPancreatic islets are important in nutrient homeostasis and improved cellular models of clonal origin may very useful especially in view of relatively scarce primary material. Close 3D contact and coupling between β-cells are a hallmark of physiological function improving signal/noise rati...

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Principais autores: Emilie Puginier, Karen Leal-Fischer, Julien Gaitan, Marie Lallouet, Pier-Arnaldo Scotti, Matthieu Raoux, Jochen Lang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Endocrinology
Fag:
spheroids
extracellular electrophysiology
microelectrode array
islets
insulin
EndoC-βH1
Online adgang:https://www.frontiersin.org/articles/10.3389/fendo.2024.1402880/full
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