Comprehensive genomic identification of essential genes required for Brucella melitensis intracellular survival during macrophage infection

Abstract Brucella melitensis is a significant zoonotic pathogen transmissible via contact, digestive, and respiratory routes, posing severe threats to livestock economies and human health. While its virulence genes critically regulate intracellular survival and replication, the molecular mechanisms...

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Detalhes bibliográficos

Principais autores:	Zhiqiang Jiang, Jiajun Gao, Mengda Liu, Xiangxiang Sun, Fei Qi, Weixing Shao, Wenlong Nan, Lu Chang, Kaihui Zhang, Xin Yan, Mingjun Sun, Shufang Sun, Xiaoxu Fan, Haobo Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-03-01
coleção:	Scientific Reports
Assuntos:	Brucella melitensis TraDIS Virulence genes Macrophages
Acesso em linha:	https://doi.org/10.1038/s41598-026-46186-6
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