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The helicase activity of hyperthermophilic archaeal MCM is enhanced at high temperatures by lysine methylation

Lysine methylation and methyltransferases are widespread in the third domain of life, archaea. Nevertheless, the effects of methylation on archaeal proteins wait to be defined. Here, we report that recombinant sisMCM, an archaeal homolog of Mcm2-7 eukaryotic replicative helicase, is methylated by aK...

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主要な著者: Yisui eXia, Yanling eNiu, Jiamin eCui, Yang eFu, Xiaojiang eChen, Huiqiang eLou, Qinhong eCao
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2015-11-01
シリーズ:Frontiers in Microbiology
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オンライン・アクセス:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01247/full
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