Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).

Efavirenz (EFV) is among the most commonly used antiretroviral drugs globally, causes neurological symptoms that interfere with adherence and reduce tolerability, and may have central nervous system (CNS) effects that contribute in part to HIV associated neurocognitive disorders (HAND) in patients o...

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Автори:	Lecia A M Brown, Jingji Jin, Darren Ferrell, Edin Sadic, Demian Obregon, Adam J Smith, Jun Tan, Brian Giunta
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Public Library of Science (PLoS) 2014-01-01
Серія:	PLoS ONE
Онлайн доступ:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095500&type=printable
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