Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides

Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may have a protective effect. Here we analyzed distribution of a highly polymorphous HLA-DRB1 locus in more than one thous...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Azad Mamedov, Nadezhda Vorobyeva, Ioanna Filimonova, Maria Zakharova, Ivan Kiselev, Vitalina Bashinskaya, Natalia Baulina, Alexey Boyko, Alexander Favorov, Olga Kulakova, Rustam Ziganshin, Ivan Smirnov, Alina Poroshina, Igor Shilovskiy, Musa Khaitov, Yuri Sykulev, Olga Favorova, Valentin Vlassov, Alexander Gabibov, Alexey Belogurov
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2020-01-01
سلاسل:	Frontiers in Immunology
الموضوعات:	myelin basic protein multiple sclerosis human leukocyte antigen protective allele epitope library hemagglutinin
الوصول للمادة أونلاين:	https://www.frontiersin.org/article/10.3389/fimmu.2019.03088/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!