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Adenosine Depletion as A New Strategy to Decrease Glioblastoma Stem-Like Cells Aggressiveness

Glioblastoma is the brain tumor with the worst prognosis. This is mainly due to a cell subpopulation with an extremely aggressive potential, called glioblastoma stem-like cells (GSCs). These cells produce high levels of extracellular adenosine, which are increased even more under hypoxic conditions....

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ignacio Niechi, Atenea Uribe-Ojeda, José Ignacio Erices, Ángelo Torres, Daniel Uribe, José Dellis Rocha, Pamela Silva, Hans G. Richter, Rody San Martín, Claudia Quezada
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-10-01
Schriftenreihe:Cells
Schlagworte:
glioblastoma
adenosine
invasiveness
stemness
adenosine deaminase
Online-Zugang:https://www.mdpi.com/2073-4409/8/11/1353
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