A novel subunit vaccine based on Fiber1/2 knob domain provides full protection against fowl adenovirus serotype 4 and induces stronger immune responses than a Fiber2 subunit vaccine

ABSTRACT: Outbreaks of hepatitis-hydropericardium syndrome (HHS) caused by fowl adenovirus serotype 4 (FAdV-4) have resulted in huge economic losses to the poultry industry in China since 2015. However, commercially available vaccines against the FAdV-4 infection remain scarce. In our study, subunit...

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Autori principali:	Shuaifeng Liu, Xiaofeng Dong, Baishi Lei, Wuchao Zhang, Xiangqin Wang, Wanzhe Yuan, Kuan Zhao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-08-01
Serie:	Poultry Science
Soggetti:	FAdV-4 Fiber1 knob domain Fiber2 knob domain subunit vaccine efficacy
Accesso online:	http://www.sciencedirect.com/science/article/pii/S003257912400467X
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