Absorption, metabolism, and excretion of [14C]dersimelagon, an investigational oral selective melanocortin 1 receptor agonist, in preclinical species and healthy volunteers

Abstract Dersimelagon (formerly MT‐7117) is a novel, orally administered nonpeptide small molecule selective agonist for melanocortin 1 receptor currently being investigated for the treatment of erythropoietic protoporphyria, X‐linked protoporphyria, and diffuse cutaneous systemic sclerosis (dcSSc)....

Celý popis

Podrobná bibliografie

Hlavní autoři:	Minoru Tsuda, Kei Ogawa, Tadashi Endou, Takahiro Goto, Yuko Ogasawara, Akihito Ogasawara
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2023-06-01
Edice:	Pharmacology Research & Perspectives
Témata:	absorption dersimelagon erythropoietic protoporphyria excretion metabolism X‐linked protoporphyria
On-line přístup:	https://doi.org/10.1002/prp2.1084
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!