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pyTCR: A comprehensive and scalable solution for TCR-Seq data analysis to facilitate reproducibility and rigor of immunogenomics research

T cell receptor (TCR) studies have grown substantially with the advancement in the sequencing techniques of T cell receptor repertoire sequencing (TCR-Seq). The analysis of the TCR-Seq data requires computational skills to run the computational analysis of TCR repertoire tools. However biomedical re...

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Principais autores: Kerui Peng, Jaden Moore, Mohammad Vahed, Jaqueline Brito, Guoyun Kao, Amanda M. Burkhardt, Houda Alachkar, Serghei Mangul
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-10-01
Serier:Frontiers in Immunology
Fag:
TCR - T cell receptor
TCR-seq
immunogenomics
computational notebooks
TCR characterization
reproducibility
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.954078/full
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