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Receptor-Mediated SPION Labeling of CD4<sup>+</sup> T Cells for Longitudinal MRI Tracking of Distribution Following Systemic Injection in Mouse

Tracking T cells in vivo using MRI is a major challenge due to the difficulty of labeling these non-phagocytic cells with a sufficient contrast agent to generate a detectable signal change. In this study, we explored CD4-Superparamagnetic iron oxide nanoparticles (SPION), which is commonly used in m...

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Principais autores: Yu Ping, Songyue Han, Brock Howerton, Francesc Marti, Jake Weeks, Roberto Gedaly, Reuben Adatorwovor, Fanny Chapelin
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2025-07-01
סדרה:Nanomaterials
נושאים:
CD4<sup>+</sup> T cells
SPION
MRI
magnetic-activated cell sorting
immunomodulation
transplantation
גישה מקוונת:https://www.mdpi.com/2079-4991/15/14/1068
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