Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on the Cystic Fibrosis Airway Microbial Metagenome

ABSTRACT The introduction of mutation-specific combination therapy with the cystic fibrosis transmembrane conductance regulator (CFTR) modulators elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) has substantially improved lung function and quality of life of people with cystic fibrosis (CF). Collectin...

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Autors principals:	Sophia T. Pallenberg, Marie-Madlen Pust, Ilona Rosenboom, Gesine Hansen, Lutz Wiehlmann, Anna-Maria Dittrich, Burkhard Tümmler
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2022-10-01
Col·lecció:	Microbiology Spectrum
Matèries:	CFTR modulation ELX/TEZ/IVA airway metagenome cystic fibrosis metagenomics whole-genome sequencing
Accés en línia:	https://journals.asm.org/doi/10.1128/spectrum.01454-22
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