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AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin

GH (growth hormone) secretion/action is modulated by alterations in energy homeostasis, such as malnutrition and obesity. Recent data have uncovered the mechanism by which hypothalamic neurons sense nutrient bioavailability, with a relevant contribution of AMPK (AMP-activated protein kinase) and mTO...

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Detalhes bibliográficos
Principais autores: María J. Vázquez, Marta G. Novelle, Francisca Rodríguez-Pacheco, Ricardo Lage, Luis Varela, Miguel López, Leonor Pinilla, Manuel Tena-Sempere, Carlos Diéguez
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
coleção:Cells
Assuntos:
Acesso em linha:https://www.mdpi.com/2073-4409/9/9/1940
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