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Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting

ABSTRACT Sclerostin antibody (romosozumab) was recently approved for clinical use in the United States to treat osteoporosis. We and others have explored Wnt‐based combination therapy to disproportionately improve the anabolic effects of sclerostin inhibition, including cotreatment with sclerostin a...

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Autors principals: Roy B Choi, Whitney A Bullock, April M Hoggatt, Gabriela G Loots, Damian C Genetos, Alexander G Robling
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021-05-01
Col·lecció:JBMR Plus
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Accés en línia:https://doi.org/10.1002/jbm4.10462
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