Clonorchis sinensis granulin promotes malignant transformation of human intrahepatic biliary epithelial cells through interaction with M2 macrophages via regulation of STAT3  phosphorylation and the MEK/ERK pathway

Abstract Background Clonorchis sinensis granulin (CsGRN), a component of the excretory/secretory products of this species, is a multifunctional growth factor that can promote the metastasis of cholangiocarcinoma cells. However, the effect of CsGRN on human intrahepatic biliary epithelial cells (HIBE...

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Autores principales:	Qing He, Xiaowen Pan, Yingxuan Yin, Anyuan Xu, Xueqing Yi, Yinjuan Wu, Xuerong Li
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-04-01
Colección:	Parasites & Vectors
Materias:	Clonorchis sinensis granulin Malignant transformation M2 macrophages STAT3 phosphorylation MEK/ERK signaling pathway
Acceso en línea:	https://doi.org/10.1186/s13071-023-05765-6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!