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Jump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug Transporter.

ABCG2/BCRP is a membrane protein, involved in xenobiotic and endobiotic transport in key pharmacological barriers and drug metabolizing organs, in the protection of stem cells, and in multidrug resistance of cancer. Pharmacogenetic studies implicated the role of ABCG2 in response to widely used medi...

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Détails bibliographiques
Auteurs principaux: Laura László, Balázs Sarkadi, Tamás Hegedűs
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2016-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC5065228?pdf=render
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