Multivalent MVA-vectored vaccine elicits EBV neutralizing antibodies in rhesus macaques that reduce EBV infection in humanized mice

IntroductionEpstein-Barr virus (EBV) is an oncogenic human herpesvirus associated with ~350,000 cases of lymphoid and epithelial malignancies every year, and is etiologically linked to infectious mononucleosis and multiple sclerosis. Despite four decades of research, no EBV vaccine candidate has yet...

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Hlavní autoři:	Gabriela M. Escalante, Ivana G. Reidel, Lorraine Z. Mutsvunguma, Simeon Cua, Brenda A. Tello, Esther Rodriguez, Mafalda A. Farelo, Cloe Zimmerman, Murali Muniraju, He Li, Aparna N. Govindan, Michael K. Axthelm, Scott W. Wong, Javier Gordon Ogembo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-09-01
Edice:	Frontiers in Immunology
Témata:	Epstein-Barr virus infectious mononucleosis cancer prophylactic vaccine glycoprotein neutralizing antibody
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445209/full
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