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Decoding the general role of tRNA queuosine modification in eukaryotes

Abstract Transfer RNA (tRNA) contains modified nucleosides essential for modulating protein translation. One of these modifications is queuosine (Q), which affects NAU codons translation rate. For decades, multiple studies have reported a wide variety of species-specific Q-related phenotypes in diff...

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Principais autores: Jorge Díaz-Rullo, Luis González-Moreno, Araceli Del Arco, José Eduardo González-Pastor
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-01-01
Serier:Scientific Reports
Fag:
Queuosine
tRNA modification
Translation
Gene regulation
Bioinformatics
Eukaryotes
Online adgang:https://doi.org/10.1038/s41598-024-83451-y
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