APOL1 renal risk variants exacerbate podocyte injury by increasing inflammatory stress
Abstract Background Apolipoprotein L1, APOL1, is a trypanosome lytic factor present in human and certain other primates. APOL1 gene variants, present in individuals of recent sub-Saharan African descent, increase risk for glomerular disease and associate with the disease progression, but the molecul...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-08-01
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| coleção: | BMC Nephrology |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12882-020-01995-3 |
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