Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B

Polymorphisms in genes in the human leukocyte antigen (HLA) class II region comprise the most important inherited risk factors for many autoimmune diseases, including type 1 diabetes (T1D) and celiac disease (CD): both diseases are positively associated with the HLA-DR3 haplotype (DRB1*03:01-DQA1*05...

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Bibliografski detalji

Glavni autori:	Ozkan Aydemir, Jeffrey A Bailey, Daniel Agardh, Åke Lernmark, Janelle A Noble, Agnes Andersson Svärd, Elizabeth P Blankenhorn, Hemang M Parikh, Anette-G Ziegler, Jorma Toppari, Beena Akolkar, William A Hagopian, Marian J Rewers, John P Mordes, TEDDY Study Group
Format:	Artigo
Jezik:	Inglês
Izdano:	eLife Sciences Publications Ltd 2026-02-01
Serija:	eLife
Teme:	T1D diabetes celiac disease complement
Online pristup:	https://elifesciences.org/articles/89068
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