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Niosomal nanocarriers for gemcitabine in treatment of MDA-MB-231, AsPC-1 and Calu-6 cells: investigations in vitro and in vivo

Gemcitabine (GEM) is a cytotoxic chemotheraputic agent employed for treatment of different cancers. GEM-loaded nanoniosomes were synthesized and characterized to enhance efficacy and weaken its side effects by decreasing half-maximal inhibitory concentration (IC50) value. The nanoniosomes were prepa...

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Hlavní autoři: Aliyeh Ranjbar, Mohammadreza Ajdari, Khashayar Karimian, Maryam Karimi, Hossein Heli, Naghmeh Sattarahmady
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2026-02-01
Edice:Heliyon
Témata:
Niosome
Drug delivery
Gemzar®
Nanocarrier
Surfactant vesicles
Antitumor
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2405844026000356
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