An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo

Abstract Background Restraining or slowing ageing hallmarks at the cellular level have been proposed as a route to increased organismal lifespan and healthspan. Consequently, there is great interest in anti-ageing drug discovery. However, this currently requires laborious and lengthy longevity analy...

Descripció completa

Dades bibliogràfiques

Autors principals:	Celia Lujan, Eleanor Jane Tyler, Simone Ecker, Amy Philomena Webster, Eleanor Rachel Stead, Victoria Eugenia Martinez-Miguel, Deborah Milligan, James Charles Garbe, Martha Ruskin Stampfer, Stephan Beck, Robert Lowe, Cleo Lucinda Bishop, Ivana Bjedov
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-07-01
Col·lecció:	Genome Medicine
Matèries:	Senescence CellPopAge epigenetic Clock Drug discovery Ageing CpG methylation Rapamycin
Accés en línia:	https://doi.org/10.1186/s13073-024-01349-w
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!