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Synthesis of Polycyclic Ether-Benzopyrans and In Vitro Inhibitory Activity against <i>Leishmania tarentolae</i>

Construction of a focused library of polycyclic ether-benzopyrans was undertaken in order to discover new therapeutic compounds that affect <i>Leishmania</i> growth and infectivity. This is especially of interest since there are few drug therapies for leishmaniasis that do not have serious drawbacks...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sarita Singh, Jacob P. Grabowski, Shilpa Pohani, C. Fiore Apuzzo, David C. Platt, Marjorie A. Jones, T. Andrew Mitchell
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-11-01
Schriftenreihe:Molecules
Schlagworte:
oxidopyrylium
cycloaddition
Suzuki-Miyaura
benzopyran
oxabicyclo[3.2.1]-octane
Leishmania
Online-Zugang:https://www.mdpi.com/1420-3049/25/22/5461
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