Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

Recent studies have demonstrated that many parasites release extracellular vesicles (EVs), yet little is known about the specific interactions of EVs with immune cells or their functions during infection. We show that EVs secreted by the gastrointestinal nematode Heligmosomoides polygyrus are intern...

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Autori principali:	Gillian Coakley, Jana L. McCaskill, Jessica G. Borger, Fabio Simbari, Elaine Robertson, Marissa Millar, Yvonne Harcus, Henry J. McSorley, Rick M. Maizels, Amy H. Buck
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2017-05-01
Serie:	Cell Reports
Soggetti:	extracellular vesicle helminth macrophage alternative activation host-pathogen vaccination
Accesso online:	http://www.sciencedirect.com/science/article/pii/S221112471730606X
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