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Redox-Sensitive Linear and Cross-Linked Cystamine-Based Polymers for Colon-Targeted Drug Delivery: Design, Synthesis, and Characterisation

Cystamine-based polymers may help to achieve controlled and targeted drug delivery to the colon due to their susceptibility to breakage of the disulfide linkage in the low redox potential environment of the colon. In this study, two linear cystamine-based polymers with similar repeating units (LP1 a...

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Main Authors: Yoke Mooi Ng, Siti Nur Aishah Mat Yusuf, Hock Ing Chiu, Vuanghao Lim
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-05-01
Series:Pharmaceutics
Subjects:
redox-sensitive
linear
crosslinked
disulfide
thiol
cystamine
Online Access:https://www.mdpi.com/1999-4923/12/5/461
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