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Rapid gain and loss of a chromosome drives key morphology and virulence phenotypes in the fungal pathogen Histoplasma.

Heritable phenotypic switches are fundamental to the ability of cells to respond to specific conditions. Such switches are key to the success of environmental pathogens, which encounter disparate conditions as they transition between the environment and host. We determine that the copy number of chr...

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מידע ביבליוגרפי
Principais autores: Sarah Heater, Mark Voorhies, Rosa A Rodriguez, Bevin C English, Anita Sil
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2026-01-01
סדרה:PLoS Biology
גישה מקוונת:https://doi.org/10.1371/journal.pbio.3003224
תגים: הוספת תג
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