Altered glia-neuron communication in Alzheimer’s Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq

Abstract Background Alzheimer’s disease is the most common cause of dementia and is characterized by amyloid-β plaques, tau neurofibrillary tangles, and neuronal loss. Although neuronal loss is a primary hallmark of Alzheimer’s disease, it is known that non-neuronal cell populations are ultimately r...

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Bibliografiska uppgifter

Huvudupphov:	Tabea M. Soelter, Timothy C. Howton, Amanda D. Clark, Vishal H. Oza, Brittany N. Lasseigne
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2024-06-01
Serie:	Cell Communication and Signaling
Ämnen:	Alzheimer’s disease Neurodegeneration Cell-cell communication Signaling Single-cell Networks
Länkar:	https://doi.org/10.1186/s12964-024-01686-8
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