Circadian clock-gut microbiota axis in pulmonary hypertension: linking gut–lung crosstalk, immune timing and vascular remodeling

Pulmonary hypertension (PH) is a severe disorder characterized by progressive pulmonary vascular remodeling, increased pulmonary arterial pressure, and right heart failure. Beyond local abnormalities within the pulmonary vasculature, growing evidence suggests that PH is shaped by systemic inflammati...

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Hlavní autoři:	Ruixian Wu, Shuang Fu, Yiwen Zhang, Yuanyuan Dong, Jian Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-07-01
Edice:	Frontiers in Physiology
Témata:	chronopharmacology circadian rhythm gut microbiota gut-lung axis immune inflammation microbial metabolites
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphys.2026.1895249/full
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