Computational fragment-based drug design of potential Glo-I inhibitors
In this study, a fragment-based drug design approach, particularly de novo drug design, was implemented utilising three different crystal structures in order to discover new privileged scaffolds against glyoxalase-I enzyme as anticancer agents. The fragments were evoluted to indicate potential inhib...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis Group
2024-12-01
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| Schriftenreihe: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Schlagworte: | |
| Online-Zugang: | https://www.tandfonline.com/doi/10.1080/14756366.2024.2301758 |
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