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Suppression of quercetin-induced autophagy enhances cytotoxicity through elevating apoptotic cell death in human bladder cancer cells

Objective: Quercetin, a natural dietary compound, has been demonstrated with antitumor activities against several types of cancers by disrupting cell cycle and inducing apoptotic cell death. However, human bladder cancer cells such as 5637 and T24 cells expressing mutant p53 are resistant to a 24 hr...

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Principais autores: Te-Fu Tsai, Thomas I-Sheng Hwang, Ji-Fan Lin, Hung-En Chen, Shan-Che Yang, Yi-Chia Lin, Kuang-Yu Chou
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health/LWW 2019-01-01
coleção:Urological Science
Assuntos:
Apoptosis
autophagy
bladder cancer
quercetin
reactive oxygen species
Acesso em linha:http://www.e-urol-sci.com/article.asp?issn=1879-5226;year=2019;volume=30;issue=2;spage=58;epage=66;aulast=Tsai
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