NAC, NAC, Knockin’ on Heaven's door: Interpreting the mechanism of action of N-acetylcysteine in tumor and immune cells

N-acetylcysteine (NAC) has been used as a direct scavenger of reactive oxygen species (hydrogen peroxide, in particular) and an antioxidant in cancer biology and immuno-oncology. NAC is the antioxidant drug most frequently employed in studies using tumor cells, immune cells, and preclinical mouse xe...

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Detalhes bibliográficos

Autor principal:	Balaraman Kalyanaraman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-11-01
coleção:	Redox Biology
Assuntos:	Mitochondrial reactive oxygen species Ferroptosis Fluorescent probes Transferrin iron Tumor metastasis Antioxidant thiols
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231722002695
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