A yeast model of FUS/TLS-dependent cytotoxicity.
FUS/TLS is a nucleic acid binding protein that, when mutated, can cause a subset of familial amyotrophic lateral sclerosis (fALS). Although FUS/TLS is normally located predominantly in the nucleus, the pathogenic mutant forms of FUS/TLS traffic to, and form inclusions in, the cytoplasm of affected s...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science (PLoS)
2011-04-01
|
| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC3082520?pdf=render |
| Tags: |
No Tags, Be the first to tag this record!
|