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HB-EGF upregulates StAR expression and stimulates progesterone production through ERK1/2 signaling in human granulosa-lutein cells

Abstract Background Heparin-binding epidermal growth factor-like growth factor (HB-EGF) belongs to the epidermal growth factor (EGF) family of growth factors. HB-EGF and its receptors, epidermal growth factor receptor (EGFR) and HER4, are expressed in the human corpus luteum. HB-EGF has been shown t...

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Príomhchruthaitheoirí: Jung-Chien Cheng, Xiaoyu Han, Qingxue Meng, Yanjie Guo, Boqun Liu, Tinglin Song, Yuanyuan Jia, Lanlan Fang, Ying-Pu Sun
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2022-10-01
Sraith:Cell Communication and Signaling
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12964-022-00983-4
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