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Are off-target effects of imatinib the key to improving beta-cell function in diabetes?

The small tyrosine kinase (TK) inhibitor imatinib mesylate (Gleevec, STI571) protects against both type 1 and type 2 diabetes, but as it inhibits many TKs and other proteins, it is not clear by which mechanisms it acts. This present review will focus on the possibility that imatinib acts, at least i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Nils Welsh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Upsala Medical Society 2022-09-01
Cyfres:Upsala Journal of Medical Sciences
Pynciau:
Mynediad Ar-lein:https://ujms.net/index.php/ujms/article/view/8841/14851
Tagiau: Ychwanegu Tag
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