Direct Differentiation of Human Adult Adipose Tissue into Multilineage Functional Organoids

Current organoid-generation strategies rely predominantly on intricate in vitro manipulations of dissociated stem cells, including isolation, expansion, and genetic modification. However, these approaches present significant challenges in terms of safety and scalability for clinical applications. An...

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Autori principali:	Ru-Lin Huang, Jing Yang, Yuxin Yan, Xiangqi Liu, Xiya Yin, Chuanqi Liu, Xingran Liu, Rehanguli Aimaier, Qiumei Ji, Gen Li, Tao Zan, Kang Zhang, Qingfeng Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-10-01
Serie:	Engineering
Soggetti:	Tissue regeneration Regenerative medicine Human adipose tissue Islet organoids Bone marrow organoids Neuroectoderm differentiation
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2095809925003595
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