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Population Pharmacokinetics and Exposure‐Response Analysis of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia Patients With NPM1 Mutation

ABSTRACT Ziftomenib, a potent, highly selective, oral menin inhibitor, has demonstrated significant clinical benefit and deep responses in relapsed and/or refractory (R/R) nucleophosmin 1‐mutated (NPM1‐m) acute myeloid leukemia (AML) patients. Here we present data from analyses conducted to characte...

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Autori principali: Amitava Mitra, Xiaoyan Yang, Roberto H. Ortiz, Claudia Jomphe, Mollie Leoni, Nathalie H. Gosselin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2026-05-01
Serie:CPT: Pharmacometrics & Systems Pharmacology
Accesso online:https://doi.org/10.1002/psp4.70244
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