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Insulin-like growth factor-1 signaling in the tumor microenvironment: Carcinogenesis, cancer drug resistance, and therapeutic potential

The tumor microenvironment fuels tumorigenesis and induces the development of resistance to anticancer drugs. A growing number of reports support that the tumor microenvironment mediates these deleterious effects partly by overexpressing insulin-like growth factor 1 (IGF-1). IGF-1 is known for its r...

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Principais autores: Armel H. Nwabo Kamdje, Paul F. Seke Etet, Maulilio J. Kipanyula, Lorella Vecchio, Richard Tagne Simo, Alfred K. Njamnshi, Kiven E. Lukong, Patrice N. Mimche
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-08-01
coleção:Frontiers in Endocrinology
Assuntos:
Insulin-like growth factor
tumor microenvironment
cancer
drug resistance
IGF-1
microenvironment
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2022.927390/full
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