EVOLUTIONARILY CONSERVED CATALYTIC RESIDUES IN UREASES FROM CLINICAL PSEUDOMONAS SPP. ISOLATES ARE IMPORTANT FOR INHIBITION BY ACETOHYDROXAMIC ACID
Introduction: The genus Pseudomonas includes opportunistic pathogens frequently exhibiting multidrug resistance and involved in hospital infections, in which urease remains an unexplored therapeutic target for virulence attenuation. Urease is a nickel-dependent metalloenzyme that catalyzes the hydro...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2026-03-01
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| Serier: | Brazilian Journal of Infectious Diseases |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S1413867026001030 |
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