Ability to form Sox17-induced hematopoietic cell clusters varies among distinct hematopoietic sites during development

Abstract Background Definitive hematopoietic stem cells (HSCs) emerge within intra-aortic hematopoietic cell clusters (IAHCs) located in the dorsal aorta of the aorta-gonad-mesonephros (AGM) region during midgestation in the mouse embryo. Thereafter, HSCs migrate to the fetal liver (FL) and finally...

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Principais autores:	Ayumi Itabashi, Yuki Yokoi, Kiyoka Saito, Ryota Tsukahara, Gerel Melig, Koya Azuma, Naoki Iizuka, Tetsuya Taga, Ikuo Nobuhisa
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-04-01
Series:	Inflammation and Regeneration
Assuntos:	Hematopoiesis HSPC Sox17 IAHCs Procr
Acceso en liña:	https://doi.org/10.1186/s41232-026-00420-w
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