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In vitro HIV-1 LTR integration into T-cell activation gene CD27 segment and the decoy effect of modified-sequence DNA.

Integration into the host genome is an essential step in the HIV-1 life cycle. However, the host genome sequence that is favored by HIV-1 during integration has never been documented. Here, we report that CD27, a T cell activation gene, includes a sequence that is a target for in vitro HIV-1 cDNA in...

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Principais autores: Rei Ohmori, Tatsuaki Tsuruyama
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3509153?pdf=render
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