Evaluation of magnetic resonance spectroscopy total sodium concentration measures, and associations with microstructure and physical impairment in cervical myelopathy

Abstract Spinal cord injury causes a cascade of physiological responses, which may trigger a subsequent neurotoxic increase in intracellular sodium. This can lead to neurodegeneration, both at and beyond the site of injury, causing clinical symptoms and loss of function. However, in vivo measurement...

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Autori principali:	Bhavana S. Solanky, Ferran Prados, Carmen Tur, Francesco Grussu, Selma Al-Ahmad, Xixi Yang, Alessia Bianchi, Baris Kanber, Antonino Russo, Vittorio Russo, David Choi, Jalesh N. Panicker, Claudia A. M. Gandini Wheeler-Kingshott
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-02-01
Serie:	Scientific Reports
Soggetti:	Spinal cord Sodium MRS NODDI Cervical myelopathy ASIA score Macromolecular tissue volume
Accesso online:	https://doi.org/10.1038/s41598-025-91658-w
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