WQ-3810, a fluoroquinolone with difluoropyridine derivative as the R1 group exerts high potency against quinolone-resistant Campylobacter jejuni

ABSTRACT Quinolone-resistant Campylobacter jejuni have been increasing worldwide. Quinolones exert their antibacterial activity by inhibiting DNA gyrase, but most of the isolates acquire quinolone resistance via an amino acid substitution in the A subunit of DNA gyrase. WQ-3810 is a quinolone antibi...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Kentaro Koide, Hyun Kim, Matthew V. X. Whelan, Lawrence P. Belotindos, Wimonrat Tanomsridachchai, Ruchirada Changkwanyeun, Masaru Usui, Tadhg Ó Cróinín, Jeewan Thapa, Chie Nakajima, Yasuhiko Suzuki
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology 2024-10-01
श्रृंखला:	Microbiology Spectrum
विषय:	antimicrobial resistance quinolone Campylobacter jejuni DNA gyrase
ऑनलाइन पहुंच:	https://journals.asm.org/doi/10.1128/spectrum.04322-23
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