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The rarA gene as part of an expanded RecFOR recombination pathway: Negative epistasis and synthetic lethality with ruvB, recG, and recQ.

The RarA protein, homologous to human WRNIP1 and yeast MgsA, is a AAA+ ATPase and one of the most highly conserved DNA repair proteins. With an apparent role in the repair of stalled or collapsed replication forks, the molecular function of this protein family remains obscure. Here, we demonstrate t...

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Autori principali: Kanika Jain, Elizabeth A Wood, Michael M Cox
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2021-12-01
Serie:PLoS Genetics
Accesso online:https://doi.org/10.1371/journal.pgen.1009972
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