RNA-seq data exploration after trypanosome RNA-binding protein UBP1 expression is altered by CRISPR-Cas9 gene editing and overexpression

Previous studies have shown that overexpression of the Trypanosoma cruzi U-rich RNA-binding protein 1 (TcUBP1) in insect-dwelling epimastigotes results in a gene expression pattern resembling that of the infective form of the pathogen. Here, we used CRISPR-Cas9-induced edition of TcUBP1 and full-len...

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Principais autores:	Karina B. Sabalette, Vanina A. Campo, José R. Sotelo-Silveira, Pablo Smircich, Javier G. De Gaudenzi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-04-01
coleção:	Data in Brief
Assuntos:	RNA-binding protein Transcriptomics Trypanosoma cruzi Differential gene expression Parasite differentiation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352340924001276
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