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First-in-human infection imaging with 89Zr-labelled leukocytes and comparison of scan quality with [99mTc]Tc-HMPAO-labelled leukocytes

IntroductionNuclear medicine infection imaging is routinely performed with the use of leukocytes radiolabelled with technetium-99m hexamethylpropyleneamine oxime ([99mTc]Tc-HMPAO) and single-photon emission computed tomography (SPECT). Positron emission tomography (PET) is more sensitive than SPECT...

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Auteurs principaux: Maryke Kahts, Beverley Summers, Akhona Nkokheli Ndlela, Aadil Gutta, Phumudzo Nemutaduni, Andrew More, Aman Parsoo, Thomas Ebenhan, Jan Rijn Zeevaart, Omer Aras, Mike Machaba Sathekge
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2024-07-01
Collection:Frontiers in Nuclear Medicine
Sujets:
infection imaging
inflammation
[99mTc]Tc-HMPAO
labelled leukocytes
WBC scan
zirconium-89
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fnume.2024.1426650/full
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