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Summarizing attributable factors and evaluating risk of bias of Mendelian randomization studies for Alzheimer’s dementia and cognitive status: a systematic review and meta-analysis

Abstract Background No effective treatment is available to delay or reverse the onset and progression of Alzheimer’s dementia (AD). Mild cognitive impairment, a clinical state between normal aging and AD, may offer the proper window for AD intervention and treatment. This systematic review aimed to...

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Principais autores: Xiaoni Meng, Xiaochun Li, Meiling Cao, Jing Dong, Haotian Wang, Weijie Cao, Di Liu, Youxin Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-03-01
Serier:Systematic Reviews
Fag:
Alzheimer’s dementia
Cognitive status
Modifiable factors
Mendelian randomization
Systemic review
Risk of bias
Online adgang:https://doi.org/10.1186/s13643-025-02792-5
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