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Selinexor and the Selective Inhibition of Nuclear Export: A New Perspective on the Treatment of Sarcomas and Other Solid and Non-Solid Tumors

Nucleocytoplasmic transport has been found dysregulated in many types of cancer and is often described as a poor prognostic factor. Specifically, Exportin-1 (XPO1) has been found overexpressed in many tumors and has become an attractive target in molecular oncology and therapeutics development. The...

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Váldodahkkit: Antonella Lucia Marretta, Giuseppe Di Lorenzo, Dario Ribera, Lucia Cannella, Claudia von Arx, Alessandra Bracigliano, Ottavia Clemente, Roberto Tafuto, Antonio Pizzolorusso, Salvatore Tafuto
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2021-09-01
Ráidu:Pharmaceutics
Fáttát:
Liŋkkat:https://www.mdpi.com/1999-4923/13/9/1522
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