A novel parC mutation potentiating fluoroquinolone resistance in Klebsiella pneumoniae and Escherichia coli clinical isolates

Introduction: Resistance to fluoroquinolones is mainly due to point mutations that gave rise to amino acid substitutions in the quinolone resistance-determining regions of either gyrA or parC genes, which may be augmented by plasmid mediated resistance. Accordingly, the main aim of the study was to...

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Autori principali: Marwa Atef Yakout, Ghada Hani Ali
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Journal of Infection in Developing Countries 2022-02-01
Serie:Journal of Infection in Developing Countries
Soggetti:
Klebsiella pneumonia
Escherichia coli
gyrA
parC
Fluoroquinolones
Mutations
Accesso online:https://jidc.org/index.php/journal/article/view/15142
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