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Ad26.RSV.preF completely protects calves from severe respiratory disease induced by bovine RSV challenge

Abstract Vaccination with Ad26.RSV.preF, an Adenoviral serotype 26 vector encoding RSV F protein stabilized in its prefusion conformation, has previously shown to be immunogenic and protective in RSV seropositive adults and immunogenic in seropositive infants. Human and bovine RSV (bRSV) are genetic...

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Autori principali: Leslie van der Fits, Rineke de Jong, Karin Dijkman, Marjolein Heemskerk-van der Meer, Lisanne Tettero, Judith Bonsing, Sophie van Oort, Jan Serroyen, Marianke van Schie, Norbert Stockhofe-Zurwieden, Benoit Callendret, Roland Zahn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-11-01
Serie:npj Vaccines
Accesso online:https://doi.org/10.1038/s41541-024-01024-6
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